Nutrapharmaceutical Attributes of Different Aerial Parts of Commiphora wightii

This study aims to evaluate the extract potential of leaf, bark, and fruit of Commiphora wightii using various solvents and extraction methods. The crude concentrated extracts (CCEs) obtained from the fruit, leaves, and bark of C. wightii exhibited yields ranging from 14.08-10.63, 8.98-6.17, and 7.74-5.04 mg/g of dry weight, respectively. These CCEs showed significant amounts of total phenolic and flavonoid content ranging from 2.84-4.71 GAE (mg/g) and 1.97-3.61 CE (mg/g) in fruit extracts, 2.57-4.13 GAE (mg/g) and 1.93-3.28 CE (mg/g) in leaf extracts, 2.37-3.97 GAE (mg/g) and 1.81-3.01 CE (mg/g) in bark extracts. Additionally, these extracts demonstrated strong inhibitory effects (72-91%) on the peroxidation process in the linoleic system. Antibacterial assays revealed that Bacillus pumilus was the most sensitive microorganism, with inhibition zones ranging from 2-16 mm. Fusarium oxysporum and Aspergillus niger showed varying sensitivity, with minimum inhibitory concentration where values indicating effective antifungal activity, particularly in the fruit extracts. This study highlights the potential of C. wightii as a natural resource of antioxidants and antimicrobial agents, with the fruit extracts demonstrating the most pronounced bioactivity. These findings offer appreciated perceptions of using C. wightii to develop natural drug products with health benefits.