ABSTRACT:

In the current era of advancement in science and technology, the microbial resistance against synthetic medication is alarming due to its harmful effect on the human body; therefore, researchers are now focusing on plant-derived bioactive compounds or the use of their extracts. The extract of the plants contains diverse valuable bioactive compounds which found effective in controlling infectious diseases. The activities of these bioactive components are directly related to the antimicrobial and antioxidant activities of those bioactive compounds present in the extract of plant extract. For this purpose, two herbal plants Antirrhinum majus, & Dodonaea viscosa were collected from the Karachi Sea side region to investigate their antimicrobial activities in their methanolic extracts. The minimum inhibitory count was found effective in the determination of antimicrobial activities of extracts. Results showed that maximum inhibitory count was measured for Staphylococcus aureus and Bacillus cereus while lower for Escherichia coli, Klebsiella numoneae, and Salmonella enterica. It indicates that these plants contain bioactive compounds which can be extracted as future bio-medications.