The Journal Advances of Nutrition Science and Technology

Review Article | Open Access
Volume 5 | Issue 3-4  | Paper 15 |  https://doi.org/10.15228/ANST.2025.v05.i03-4.p15

Nutritional Determinants of Health and Disease: A Review of Diet’s Role in Inflammation, Body Composition, and Cancer Care

Mehwish Rafiq
National Institute of Food Science & Technology, University of Agriculture, Faisalabad, Pakistan

Faiza Akhtar
National Institute of Food Science & Technology, University of Agriculture, Faisalabad, Pakistan

The University of Agriculture, Peshawar, Medical University, Institute of Health Sciences, Islamabad, Pakistan

Laraib Asghar
National Institute of Food Science & Technology, University of Agriculture, Faisalabad, Pakistan

Faiqa Riaz
National Institute of Food Science & Technology, University of Agriculture, Faisalabad, Pakistan

Armaghan Ali Saad
Department of Biosciences, COMSATS University Islamabad, Pakistan

Muhammad Imran
Department of Pharmacy, University of the Punjab, Lahore, Pakistan

Muhammad Farhan
Department of Human Nutrition and Dietetics, Pir Mehr Ali Shah ARID Agriculture University, Rawalpindi, Pakistan

Umeed Ullah Ghaznawi
Department of Pharmacy, Punjab University College of Pharmacy, Lahore, Pakistan

Muhammad Sajjad
Department of Human Nutrition & Dietetics, The Islamia University of Bahawalpur, Pakistan

Muhammad Azeem
National Institute of Food Science & Technology, University of Agriculture, Faisalabad, Pakistan

Received
20 Oct, 2025
Accepted
03 Nov, 2025
Published
10 Nov, 2025

ABSTRACT:

This review hypothesizes that evidence-based dietary interventions play a fundamental, rather than auxiliary, role in maintaining health and managing disease, particularly in the context of cancer care. It highlights the critical importance of nutrition as a modifiable factor in determining health and disease. The review examines how dietary habits impact systemic inflammation and body composition, two factors that significantly influence cancer risk, treatment tolerance, and patient outcomes. Evidence suggests that pro-inflammatory nutritional patterns, such as the Western diet, are associated with elevated inflammatory biomarkers and an increased risk of disease. Conversely, anti-inflammatory diets, including the Mediterranean and Dietary Approaches to Stop Hypertension (DASH) diets, promote metabolic homeostasis and improved clinical outcomes. Nutrition also regulates body composition, helping to mitigate sarcopenia and obesity in cancer patients, both of which influence prognosis and quality of life. To integrate nutritional care into oncology practice effectively, early nutritional screening, personalized diet planning, and the inclusion of registered nutritionists within multidisciplinary teams are essential. Future research should aim to elucidate the molecular pathways linking diet to cancer progression and to refine individualized nutrition strategies in standard oncologic care.

How to Cite this paper?

APA-7 Style

Rafiq M., Akhtar F., Asghar L., Riaz F., Saad A. A., Imran M., Farhan M., Ghaznawi U. U., Sajjad M., Azeem M., (2025) Nutritional Determinants of Health and Disease: A Review of Diet’s Role in Inflammation, Body Composition, and Cancer Care Journal Advances of Nutrition Science and Technology, 5(3-4), 112-120. https://doi.org/10.15228/ANST.2025.v05.i03-4.p15.

ACS Style

M.Rafiq, F.Akhtar, L. Asghar, F. Riaz, A. A. Saad, M. Imran, M. Farhan, U. U. Ghaznawi, M. Sajjad, M. Azeem Nutritional Determinants of Health and Disease: A Review of Diet’s Role in Inflammation, Body Composition, and Cancer Care Journal Advances of Nutrition Science and Technology, 5(3-4), 112-120. https://doi.org/10.15228/ANST.2025.v05.i03-4.p15.

AMA Style
M.Rafiq, F.Akhtar, L. Asghar, F. Riaz, A. A. Saad, M. Imran, M. Farhan, U. U. Ghaznawi, M. Sajjad, M. Azeem Nutritional Determinants of Health and Disease: A Review of Diet’s Role in Inflammation, Body Composition, and Cancer Care Journal Advances of Nutrition Science and Technology, 5(3-4), 112-120. https://doi.org/10.15228/ANST.2025.v05.i03-4.p15.

Chicago/Turabian Style
M Rafiq, F Akhtar, L Asghar, F Riaz, A A Saad, M Imran, M Farhan, U U Ghaznawi, M Sajjad, M Azeem Nutritional Determinants of Health and Disease: A Review of Diet’s Role in Inflammation, Body Composition, and Cancer Care 2025. Journal Advances of Nutrition Science and Technology, 5(3-4), 112-120. https://doi.org/10.15228/ANST.2025.v05.i03-4.p15.