Research Article | Open Access Volume 5 | Issue 1 | https://doi.org/10.15228/2015.v05.i01.p07 |
α-Glucosidase Inhibitory Constituents from Ficus bengalensis
M.A. Naveed
Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
N. Riaz
Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
M. Saleem
Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
B. Jabeen
Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
M. Ashraf
Department of Biochemistry & Biotechnology, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
U. Alam
Department of Biochemistry & Biotechnology, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
A. Jabbar
Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
| Received 07 Mar, 2015 | Accepted 22 Sep, 2015 | Published 07 Dec, 2015 |
Chromatographic purification of the methanolic extract of the aerial roots of Ficus bengalensis resulted the purifiaction of 3β-acetoxyurs-9(11),12-diene (1), a new triterpene together with lupeol (2), lupeol acetate (3), conrauidienol (4), β-sitosterol (5), alpinum isoflavone (6), methyl 4-hydroxybenzoate (7), 4-hydroxymellein (8), 4-hydroxybenzoic acid (9), p-coumaric acid (10), oleanolic acid (11) and β-sitosterol 3-O-β-D-glucopyranoside (12). These compounds (1-12) were characterized by using 1D- (1H,13C) and 2D-NMR (HMQC, HMBC, COSY, NOESY) spectroscopy and mass spectrometry (EI-MS, HR-EI-MS, FAB-MS, HRFAB-MS), and in comparison with the data reported for related compounds in literature. These isolates (1-12) showed inhibitory activity against enzyme α-glucosidase with IC50 values ranging between 26.3-297.7 µM.
How to Cite this paper?
APA-7 Style
Naveed, M.A., Riaz, N., Saleem, M., Jabeen, B., Ashraf, M., Alam, U., Jabbar, A. (2015). α-Glucosidase Inhibitory Constituents from Ficus bengalensis. Pakistan Journal of Chemistry, 5(1), 42-49. https://doi.org/10.15228/2015.v05.i01.p07
ACS Style
Naveed, M.A.; Riaz, N.; Saleem, M.; Jabeen, B.; Ashraf, M.; Alam, U.; Jabbar, A. α-Glucosidase Inhibitory Constituents from Ficus bengalensis. Pak. J. Chem. 2015, 5, 42-49. https://doi.org/10.15228/2015.v05.i01.p07
AMA Style
Naveed MA, Riaz N, Saleem M, Jabeen B, Ashraf M, Alam U, Jabbar A. α-Glucosidase Inhibitory Constituents from Ficus bengalensis. Pakistan Journal of Chemistry. 2015; 5(1): 42-49. https://doi.org/10.15228/2015.v05.i01.p07
Chicago/Turabian Style
Naveed, M., A., N. Riaz, M. Saleem, B. Jabeen, M. Ashraf, U. Alam, and A. Jabbar. 2015. “α-Glucosidase Inhibitory Constituents from Ficus bengalensis” Pakistan Journal of Chemistry 5, no. 1: 42-49. https://doi.org/10.15228/2015.v05.i01.p07
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