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Research Article | Open Access
Volume 2 | Issue 1 | Paper 03 | https://doi.org/10.15228/2012.v02.i01.p03
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An Improved Synthesis And Biological Evaluation Of Some New 4,5-dihydro-pyrazole1-Carbaldehyde Derivatives
Y.B. Vibhute
Organic Research Laboratory, P.G. Department of studies in Chemistry,
Yeshwant Mahavidyalaya Nanded – 431602 (M.S.) India
S.B. Zangade
Organic Research Laboratory, P.G. Department of studies in Chemistry,
Yeshwant Mahavidyalaya Nanded – 431602 (M.S.) India
A.T. Shinde
Organic Research Laboratory, P.G. Department of studies in Chemistry,
Yeshwant Mahavidyalaya Nanded – 431602 (M.S.) India
A.Y. Vibhute
Organic Research Laboratory, P.G. Department of studies in Chemistry,
Yeshwant Mahavidyalaya Nanded – 431602 (M.S.) India
| Received 03 Mar, 2012 |
Accepted 03 Jun, 2012 |
Published 03 Dec, 2012 |
ABSTRACT:
An improved condensation of substituted chalcones 1a-g with hydrazine hydrate and formic acid in 2-methoxyethanol to afford new series of 4,5-dihydro-pyrazole-1-carbaldehyde derivatives 2a-g. Clean reaction conditions, simple workup procedure and short reaction time giving high yields of product are notable advantages of method. All newly synthesized compounds characterized by chemical test, spectral and elemental analysis. Further, all newly synthesized compounds were screened for their antimicrobial activity. Most of these title compounds exhibited potent activity.
How to Cite this paper?
APA-7 Style
Vibhute, Y.B., Zangade, S.B., Shinde, A.T., Vibhute, A.Y. (2012). An Improved Synthesis And Biological Evaluation Of Some New 4,5-dihydro-pyrazole1-Carbaldehyde Derivatives. Pakistan Journal of Chemistry, 2(1), 18-23. https://doi.org/10.15228/2012.v02.i01.p03
ACS Style
Vibhute, Y.B.; Zangade, S.B.; Shinde, A.T.; Vibhute, A.Y. An Improved Synthesis And Biological Evaluation Of Some New 4,5-dihydro-pyrazole1-Carbaldehyde Derivatives. Pak. J. Chem. 2012, 2, 18-23. https://doi.org/10.15228/2012.v02.i01.p03
AMA Style
Vibhute YB, Zangade SB, Shinde AT, Vibhute AY. An Improved Synthesis And Biological Evaluation Of Some New 4,5-dihydro-pyrazole1-Carbaldehyde Derivatives. Pakistan Journal of Chemistry. 2012; 2(1): 18-23. https://doi.org/10.15228/2012.v02.i01.p03
Chicago/Turabian Style
Vibhute, Y., B., S. B. Zangade, A. T. Shinde, and A. Y. Vibhute. 2012. “An Improved Synthesis And Biological Evaluation Of Some New 4,5-dihydro-pyrazole1-Carbaldehyde Derivatives” Pakistan Journal of Chemistry 2, no. 1: 18-23. https://doi.org/10.15228/2012.v02.i01.p03
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