Research Article | Open Access Volume 11 | Issue 1-4 | Paper 08 | doi.org/10.15228/2021.v11.i01-4.p08 |
W. Chalouati
Laboratory of Functional Physiology and Valuation of Bio-resources (UR17ES27), Higher Institute of Biotechnology of Béja, B.P. 382-9000 Béja, University of Jendouba, Tunisia
F. Ammari
Laboratory of Organic Synthesis (Unit: 05/UR/12-05), Carthage University, Faculty of Sciences of Bizerte, 7021 Jarzouna, Bizerte, Tunisia
R. Hayder
Group of Green and Applied Organic Chemistry, Laboratory of Composite Materials and Clay Minerals, National Center for Research in Materials Science, Technopole of Borj Cedria, 8027, Soliman, Tunisia
N. Besbes
Group of Green and Applied Organic Chemistry, Laboratory of Composite Materials and Clay Minerals, National Center for Research in Materials Science, Technopole of Borj Cedria, 8027, Soliman, Tunisia
C. Girard
Laboratory of Functional Physiology and Valuation of Bio-resources (UR17ES27), Higher Institute of Biotechnology of Béja, B.P. 382-9000 Béja, University of Jendouba, Tunisia
A. Ouerghui
Laboratory of Functional Physiology and Valuation of Bio-resources (UR17ES27), Higher Institute of Biotechnology of Béja, B.P. 382-9000 Béja, University of Jendouba, Tunisia
| Received 25 Aug, 2021 | Accepted 20 Nov, 2021 | Published 10 Dec, 2021 |
ABSTRACT:
Some ecological catalysts were prepared from Tunisian clays; they have been applied in the catalytic coupling reaction of alkynes and azides to prepare bioactive heterocyclic compounds based on 1,2,3-triazoles. Clays used in this work were taken from Jebal Shib (M’dhilla) and Jebal Es Sath (between Gafsa and Metlaoui) in Gafsa at South West of Tunisia. The reaction of terminal alkynes with azides in the presence of studied catalysts was studied for 36 hours at room temperature without solvents and excitements; two isomers (1,4) and (1,5) of 1,2,3-triazoles were obtained. Generally, the (1,4) isomer was obtained with an important proportion if Cu-Pullard clay was used as a catalyst in this synthesis reaction. The studied ecological catalysts were characterized by X-ray diffraction and IR spectroscopy. Heterocyclic triazoles were analyzed by 1HNMR, 13CNMR, Infrared (IR), and Ultraviolet spectroscopy. LC-MS analyses evaluated the molecular masses of synthesized triazoles.
How to Cite this paper?
APA-7 Style
Chalouati, W., Ammari, F., Hayder, R., Besbes, N., Girard, C., Ouerghui, A. (2021). Valorization of Natural Clay as an Ecological Catalyst in The Regioselective Synthesis of Some Heterocyclic Compounds Based on 1,2,3-Triazoles. Pakistan Journal of Chemistry, 11(1-4), 48-55. https://doi.org/10.15228/2021.v11.i01-4.p08
ACS Style
Chalouati, W.; Ammari, F.; Hayder, R.; Besbes, N.; Girard, C.; Ouerghui, A. Valorization of Natural Clay as an Ecological Catalyst in The Regioselective Synthesis of Some Heterocyclic Compounds Based on 1,2,3-Triazoles. Pak. J. Chem. 2021, 11, 48-55. https://doi.org/10.15228/2021.v11.i01-4.p08
AMA Style
Chalouati W, Ammari F, Hayder R, Besbes N, Girard C, Ouerghui A. Valorization of Natural Clay as an Ecological Catalyst in The Regioselective Synthesis of Some Heterocyclic Compounds Based on 1,2,3-Triazoles. Pakistan Journal of Chemistry. 2021; 11(1-4): 48-55. https://doi.org/10.15228/2021.v11.i01-4.p08
Chicago/Turabian Style
Chalouati, W., F. Ammari, R. Hayder, N. Besbes, C. Girard, and A. Ouerghui. 2021. “Valorization of Natural Clay as an Ecological Catalyst in The Regioselective Synthesis of Some Heterocyclic Compounds Based on 1,2,3-Triazoles” Pakistan Journal of Chemistry 11, no. 1-4: 48-55. https://doi.org/10.15228/2021.v11.i01-4.p08
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