Research Article | Open Access Volume 1 | Issue 2 | Paper 07 | doi.org/10.15228/2011.v01.i02.p07 |
M.A. Jamal
Department of Chemistry, Government College University, 38030 Faisalabad, Pakistan
K. Shahzad
Department of Chemistry, Government College University, 38030 Faisalabad, Pakistan
M. Sarfraz
Department of Chemistry, Government College University, 38030 Faisalabad, Pakistan
| Received 18 Mar, 2011 | Accepted 05 Apr, 2011 | Published 05 May, 2011 |
ABSTRACT:
Partial molar volume, V0 , of Ciprofloxacin in water, 0.05 mol Kg-1 hydrochloric acid and 0.05 mol Kg-1, Iron (III) chloride solutions at 298.15 and 308.15 K was calculated from precision densities obtained from Density Sound Analyzer (DSA 5000). The data represent the smaller volume of drug in 0.05 mol Kg-1 Iron (III) chloride solution than water and 0.05 mol Kg-1 hydrochloric acid at constant temperature. The differences in volumes are interpreted as due to hydrophobicity of solutes. Relative hydrophobicities were estimated from volumes of transfer from one media to another media. The hydrophobicity of this compound also plays a key role in the drug action. The possible mechanism of drug binding with the membrane structure is also discussed.
How to Cite this paper?
APA-7 Style
Jamal, M.A., Shahzad, K., Sarfraz, M. (2011). Partial molar volume of Ciprofloxacin in water, HCl and FeCl3.6H2O at 298.15K and
308.15K. Pakistan Journal of Chemistry, 1(2), 92-95. https://doi.org/10.15228/2011.v01.i02.p07
ACS Style
Jamal, M.A.; Shahzad, K.; Sarfraz, M. Partial molar volume of Ciprofloxacin in water, HCl and FeCl3.6H2O at 298.15K and
308.15K. Pak. J. Chem. 2011, 1, 92-95. https://doi.org/10.15228/2011.v01.i02.p07
AMA Style
Jamal MA, Shahzad K, Sarfraz M. Partial molar volume of Ciprofloxacin in water, HCl and FeCl3.6H2O at 298.15K and
308.15K. Pakistan Journal of Chemistry. 2011; 1(2): 92-95. https://doi.org/10.15228/2011.v01.i02.p07
Chicago/Turabian Style
Jamal, M., A., K. Shahzad, and M. Sarfraz. 2011. “Partial molar volume of Ciprofloxacin in water, HCl and FeCl3.6H2O at 298.15K and
308.15K” Pakistan Journal of Chemistry 1, no. 2: 92-95. https://doi.org/10.15228/2011.v01.i02.p07
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