{"id":4131,"date":"2026-06-05T09:15:00","date_gmt":"2026-06-05T09:15:00","guid":{"rendered":"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/?p=4131"},"modified":"2026-06-11T12:53:24","modified_gmt":"2026-06-11T12:53:24","slug":"anst-0726","status":"publish","type":"post","link":"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/2026\/06\/05\/anst-0726\/","title":{"rendered":"Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4131\" class=\"elementor elementor-4131\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3d370e8 e-flex e-con-boxed e-con e-parent\" data-id=\"3d370e8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-fe74329 e-con-full e-flex e-con e-child\" data-id=\"fe74329\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-96cb217 elementor-widget elementor-widget-text-editor\" data-id=\"96cb217\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<table border=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\" align=\"center\">\n<tbody>\n<tr>\n<td>\n<div><strong>Research Article | Open Access<\/strong><\/div>\n<div class=\"item doi\"><span class=\"value\">Volume 6 | Issue 01-2&nbsp; | Paper 07 |&nbsp; <a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2026\/06\/ANST.v06.i1-2.p07.pdf\">https:\/\/doi.org\/10.15228\/ANST.2026.v06.i01-2.p07<\/a><\/span><\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><strong><b>Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study<\/b><\/strong><\/h4>\n<div class=\"row\">\n<div class=\"main_entry\">\n<p><strong>Ayesha Abrar<\/strong><br>Faculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore 54000, Pakistan<\/p>\n<p><strong>Ali Akhtar<\/strong><br>Faculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore 54000, Pakistan<\/p>\n<p><strong>Saira Saeed<\/strong><br>Faculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore 54000, Pakistan<\/p>\n<p><strong>Subhan Nawaz<\/strong><br>Faculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore 54000, Pakistan<\/p>\n<p><strong>Maryam Asif<\/strong><br>Faculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore 54000, Pakistan<\/p>\n<p><a href=\"https:\/\/orcid.org\/0000-0002-8582-4249\" target=\"_blank\" style=\"font-size: 1rem\">Waqas Akram<\/a>&nbsp;&nbsp;<\/p><p>Faculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore 54000, Pakistan<\/p>\n<table border=\"0\" width=\"93%\" cellspacing=\"0\" cellpadding=\"0\" align=\"center\">\n<tbody>\n<tr>\n<td align=\"center\" valign=\"top\"><strong>Received<\/strong><br>30 Apr, 2026<\/td>\n<td align=\"center\" valign=\"top\"><strong>Accepted<\/strong><br>01 Jun, 2026<\/td>\n<td align=\"center\" valign=\"top\"><strong>Published<\/strong><br>5 Jun, 2026<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div class=\"item abstract\">\n<p align=\"justify\"><strong>ABSTRACT:<\/strong><\/p>\n<p>Infants and pediatric patients are at high risk of adverse drug events due to irrational prescribing, polypharmacy, and medication errors. Poor nutritional status further affects growth, immunity, and treatment outcomes. The increasing use of drugs and nutraceuticals in pediatrics raises serious concerns regarding polypharmacy, drug interactions, and nutritional health. Therefore, prescription pattern studies are needed to promote rational medication use and improve the nutritional status and overall health of pediatric patients. The study aimed to assess drug and nutraceutical prescribing practices, identify potential drug-drug interactions, and determine their determinants among pediatric outpatients. A prospective observational study was conducted at a private outpatient clinic over 6 months. The study population comprised 213 pediatric patients aged 0 to 12 years. Data collection included reviewing treatment records and drug therapy. Data were collected and analyzed, and potential drug interactions were checked using the Medscape drug interaction checker.&nbsp;Analysis of prescriptions<strong><b>&nbsp;<\/b><\/strong>revealed an average of 5.37 medications per encounter. Notably, 99.1% of drugs were prescribed by brand name. Antipyretics or analgesics were prescribed most frequently (17.7%), followed by antibiotics (12.1%). A total of 78.5% of drugs were from the essential drug list. Upper respiratory tract infections were the most common diagnosis. Polypharmacy prevalence was 69.5%, with most patients receiving five or more drugs. Potential drug-drug interactions were present in 29.5% of prescriptions, with cetirizine and azithromycin being the most common drug pair involved in moderate interactions. Multivariate logistic regression identified polypharmacy as a strong predictor for drug interactions, while age and gender were not significant. Among 213 patients, 59 received nutraceuticals (31 males [52.5%], 28 females [47.5%]), with Vitamin D3 being the most prescribed nutraceutical, and no prescriptions for proteins. This study revealed a high prevalence of polypharmacy and potential drug-drug interactions among pediatric outpatients, highlighting the need for rational prescribing and careful medication monitoring. Collaborative efforts between pharmacists and pediatricians, along with regular prescription audits, are essential for promoting safe use of medications and nutraceuticals and improving the overall health and nutritional status of pediatric patients.<br><strong><b>Keywords:<\/b><\/strong> WHO prescribes indicators, polypharmacy, nutraceuticals, drug-drug interactions, prescribing patterns<\/p>\n<p><strong>How to Cite this paper?<\/strong><\/p>\n<\/div>\n<div class=\"item abstract\">\n<div class=\"csl-entry\">\n<p><strong>APA-7 Style<\/strong><br>Ayesha A., Ali A., Saira S., Subhan N., Maryam A., Waqas A., (2026) Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study<em><i>&nbsp;<\/i><\/em><a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2026\/06\/ANST.v06.i1-2.p07.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 6(1-2), 46-54<\/a>. https:\/\/doi.org\/10.15228\/ANST.2026.v06.i01-2.p07<\/p>\n<p><strong>ACS Style<\/strong><br>A. Ayesha, A. Ali, S. Saira, N. Subhan, A. Maryam, A. Waqas, <em>Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study<i>&nbsp;<\/i><\/em><a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2026\/06\/ANST.v06.i1-2.p07.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 6(1-2), 46-54<\/a>. https:\/\/doi.org\/10.15228\/ANST.2026.v06.i01-2.p07<\/p>\n<p><strong>AMA Style<\/strong><br>A. Ayesha; A. Ali; S. Saira; N. Subhan; A. Maryam; A. Waqas; Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study<a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2026\/06\/ANST.v06.i1-2.p07.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 6(1-2), 46-54<\/a>. https:\/\/doi.org\/10.15228\/ANST.2026.v06.i01-2.p07<\/p>\n<p><strong>Chicago\/Turabian Style<\/strong><br>A Ayesha, A Ali, S Saira, N Subhan, A Maryam, A Waqas, <em>Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study (2026)<i>&nbsp;<\/i><\/em><a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2026\/06\/ANST.v06.i1-2.p07.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 6(1-2), 46-54<\/a>. https:\/\/doi.org\/10.15228\/ANST.2026.v06.i01-2.p07<\/p>\n<\/div>\n<\/div>\n<div class=\"item copyright\"><a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" rel=\"license\"><img decoding=\"async\" src=\"https:\/\/i.creativecommons.org\/l\/by\/4.0\/88x31.png\" alt=\"Creative Commons License\"><\/a><\/div>\n<\/div>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-98362cb e-con-full e-flex e-con e-child\" data-id=\"98362cb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Research Article | Open Access Volume 6 | Issue 01-2&nbsp; | Paper 07 |&nbsp; https:\/\/doi.org\/10.15228\/ANST.2026.v06.i01-2.p07 Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study Ayesha AbrarFaculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore 54000, Pakistan Ali AkhtarFaculty of Pharmaceutical Sciences, University of Central Punjab, Khayaban&#8211;Jinnah Road,&nbsp;Lahore [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[34,35],"tags":[],"class_list":["post-4131","post","type-post","status-publish","format-standard","hentry","category-34","category-issue-1-2-2026"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Assessment of Prescribing Patterns, Potential Drug-Drug Interactions and Nutraceutical Use in Pediatric Patients: A Cross-Sectional Study - The Journal Advances of Nutrition Science and Technology<\/title>\n<meta name=\"robots\" content=\"index, follow, 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