{"id":3315,"date":"2025-05-16T07:39:43","date_gmt":"2025-05-16T07:39:43","guid":{"rendered":"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/?p=3315"},"modified":"2026-03-03T20:48:47","modified_gmt":"2026-03-03T20:48:47","slug":"anst-0825","status":"publish","type":"post","link":"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/2025\/05\/16\/anst-0825\/","title":{"rendered":"Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"3315\" class=\"elementor elementor-3315\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d8f363c e-flex e-con-boxed e-con e-parent\" data-id=\"d8f363c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-eeda761 e-con-full e-flex e-con e-child\" data-id=\"eeda761\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7147e12 elementor-widget elementor-widget-text-editor\" data-id=\"7147e12\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<table border=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\" align=\"center\"><tbody><tr><td><div><strong>Mini Review Article | Open Access<\/strong><\/div><div class=\"item doi\"><span class=\"value\">Volume 5 | Issue 3-4\u00a0 | Paper 08 |\u00a0 <a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2025\/11\/ANST.v05.i3-4.p08.pdf\">https:\/\/doi.org\/10.15228\/ANST.2025.v05.i03-4.p08<\/a><\/span><\/div><\/td><\/tr><\/tbody><\/table><article class=\"obj_article_details\"><h4><strong><b>Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia<\/b><\/strong><\/h4><div class=\"row\"><div class=\"main_entry\"><p><a href=\"https:\/\/orcid.org\/0009-0004-5883-4152\" target=\"_blank\" rel=\"noopener\"><strong>Hira Ayub<\/strong><\/a><br \/>Department of Food &amp; Nutrition Sciences, College of Home Economics, University of Peshawar, Khyber Pakhtunkhwa, Pakistan.<\/p><p><strong>Sidra Naheed<\/strong><br \/>Department of Food &amp; Nutrition Sciences, College of Home Economics, University of Peshawar, Khyber Pakhtunkhwa, Pakistan.<\/p><p><strong>Fazia Ghaffar<\/strong><br \/>Department of Food &amp; Nutrition Sciences, College of Home Economics, University of Peshawar, Khyber Pakhtunkhwa, Pakistan<\/p><p><strong>Ayesha Sayed<\/strong><br \/>Department of Food &amp; Nutrition Sciences, College of Home Economics, University of Peshawar, Khyber Pakhtunkhwa, Pakistan<\/p><table border=\"0\" width=\"93%\" cellspacing=\"0\" cellpadding=\"0\" align=\"center\"><tbody><tr><td align=\"center\" valign=\"top\"><strong>Received<\/strong><br \/>27 Apr, 2024<\/td><td align=\"center\" valign=\"top\"><strong>Accepted<\/strong><br \/>12 May, 2025<\/td><td align=\"center\" valign=\"top\"><strong>Published<\/strong><br \/>13 May, 2025<\/td><\/tr><\/tbody><\/table><div class=\"item abstract\"><p align=\"justify\"><strong>ABSTRACT:<\/strong><\/p><p>Diabetes mellitus is a substantial health concern worldwide, specifically Type 2 diabetes mellitus, which has become an alarming disease and has become the seventh most common disease in terms of human suffering (DALYs), with 462 million people. In Pakistan, this figure is divided according to their ages, 27.4 million for those aged 20 and over and 13.8 million for those under 20 years. T2DM is a risk factor for developing microvascular and macrovascular complications that have an adverse effect on physical and psychological health for both patients and caregivers. Various factors are involved in the prevalence of T2DM, one of which is vitamin D deficiency. Besides the role of vitamin D, it has numerous non-skeletal functions in cancer, autoimmune diseases, psoriasis, multiple sclerosis, cardiovascular disease, and type 2 diabetes. Vitamin D impacts glucose tolerance, insulin sensitivity, and pancreatic beta cell function in people at high risk for type 2 diabetes. Obesity, aging, and low physical activity are also contributing risk factors among the T2DM and vitamin D-deficient populations. In obesity, vitamin D is no longer available as it is stored in adipose tissue due to its fat-soluble properties. It is the primary cause of hypovitaminosis D. The research revealed that women are more deficient in vitamin D, and older individuals secrete more insulin after consuming glucose. Vitamin D is crucial in regulating immune functions (by enhancing monocytes to macrophage differentiation and increasing cytotoxic activities) and lipid metabolism (by enhancing fatty acid oxidation and mitochondrial metabolism) in T2DM.<\/p><h4>How to Cite this paper?<\/h4><\/div><div class=\"item abstract\"><div class=\"csl-entry\"><p><strong>APA-7 Style<\/strong><\/p><p>Ayub, H., Naheed, S., Ghaffar, F., Syed, A., Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia. <em><i>\u00a0<\/i><\/em><a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2025\/11\/ANST.v05.i3-4.p08.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 5(3-4), 59-62<\/a>. https:\/\/doi.org\/10.15228\/ANST.2025.v05.i03-4.p08<\/p><p><strong>ACS Style<\/strong><\/p><p>H. Ayub, S. Naheed, F. Ghaffar, A. Syed, Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia. <em><i>\u00a0<\/i><\/em><a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2025\/11\/ANST.v05.i3-4.p08.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 5(3-4), 59-62<\/a>. https:\/\/doi.org\/10.15228\/ANST.2025.v05.i03-4.p08<\/p><p><strong>AMA Style<\/strong><\/p><p>H Ayub, S Naheed, F Ghaffar, A Syed, <em>Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia.<\/em> <em><i>\u00a0<\/i><\/em><a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2025\/11\/ANST.v05.i3-4.p08.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 5(3-4), 59-62<\/a>. https:\/\/doi.org\/10.15228\/ANST.2025.v05.i03-4.p08<\/p><p><strong>Chicago\/Turabian Style<\/strong><\/p><p>H Ayub; S Naheed; F Ghaffar; A Syed; Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia. <em>2025 \u00a0<\/em><a href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/wp-content\/uploads\/sites\/3\/2025\/11\/ANST.v05.i3-4.p08.pdf\" target=\"_blank\" rel=\"noopener\"><em>Journal Advances of Nutrition Science and Technology<\/em>, 5(3-4), 59-62<\/a>. https:\/\/doi.org\/10.15228\/ANST.2025.v05.i03-4.p08<\/p><\/div><\/div><div class=\"item copyright\"><p><a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" rel=\"license\"><img decoding=\"async\" src=\"https:\/\/i.creativecommons.org\/l\/by\/4.0\/88x31.png\" alt=\"Creative Commons License\" \/><\/a><\/p><p>This work is licensed under a\u00a0<a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" rel=\"license\">Creative Commons Attribution 4.0 International License<\/a>.<\/p><\/div><\/div><\/div><\/article>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f25a7d8 e-con-full e-flex e-con e-child\" data-id=\"f25a7d8\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Mini Review Article | Open AccessVolume 5 | Issue 3-4\u00a0 | Paper 08 |\u00a0 https:\/\/doi.org\/10.15228\/ANST.2025.v05.i03-4.p08 Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia Hira AyubDepartment of Food &amp; Nutrition Sciences, College of Home Economics, University of Peshawar, Khyber Pakhtunkhwa, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[30,32],"tags":[],"class_list":["post-3315","post","type-post","status-publish","format-standard","hentry","category-30","category-issue-3-4-2025"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Type 2 Diabetes Mellitus and Vitamin D: A Systematic Review of the Effects of Vitamin D Deficiency on the Outcomes and Management of Hyperglycemia - The Journal Advances of Nutrition Science and Technology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/chempublishers.com\/advances-of-nutrition-science-and-technology\/2025\/05\/16\/anst-0825\/\" \/>\n<meta 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